Two new cases of severe allergic contact dermatitis caused by acetophenone azine.

An 11-year-old non-atopic football player experienced an itchy, erythematous andvesicular eruption, initially localized to both shins, in close contact with football shin pads, after having used these two or three times a week during a 3-month period. In the following 2months, the eruption spread all over the body, including the face, when he continued to play football with a jersey garment under the shin pads (Fig. 1). He also had erythematous, vesicular and scaly lesions on both soles 3 days after starting to wear new flip-flops without socks, 8months after the beginning of the dermatitis on the shins. The eczematous eruption resolved slowly with residual depigmentation under treatment with a corticosteroid cream. After the patient had recovered from the eczematous eruption, patch testing with IQ Ultra® chambers (Chemotechnique, Vellinge, Sweden) was performed on the back with the European baseline series, a plastic and glues series, and a rubber series (Chemotechnique). The patches were removed from the back after 48h. Patch tests with commercial allergens all gave negative results on day (D) 2 and D4. Patch tests with pieces of shin pads